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Family
Accession number
Description
Faimily comment
Interpro Accession
Abstract
Wikipedia
Clan summary
Number of members
Clan members
QuickGO
Literature References
Database References
Alignment
Curation
HMM build information
HMM build commands
Family Interactions

Pfam | PF01769 | Divalent cation transporter

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Family
MgtE
Accession number
PF01769
Description
Divalent cation transporter
Faimily comment
This region is the integral membrane part of the eubacterial MgtE family of magnesium transporters. Related regions are found also in archaebacterial and eukaryotic proteins. All the archaebacterial and eukaryotic examples have two copies of the region. This suggests that the eubacterial examples may act as dimers. Members of this family probably transport Mg2+ or other divalent cations into the cell. The alignment contains two highly conserved aspartates that may be involved in cation binding (Bateman A unpubl.)
Interpro Accession
Abstract
This domain is about 40 residues long and is found in a varietyof enzymes involved in bacterial cell wall degradation [ PUBMED:1352512 ]. Thisdomain may have a general peptidoglycan binding function.
Number of members
2
Clan members
Peptidase_C10; RepL
QuickGO
process:cell wall macromolecule catabolic processGO:0016998
Literature References
TitleModular design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin.
Publication AuthorJoris B, Englebert S, Chu CP, Kariyama R, Daneo-Moore L, Shockman GD, Ghuysen JM;
JournalFEMS Microbiol Lett 1992;70:257-264.
PubMed ID1352512
 
TitleThe structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD).
Publication AuthorBateman A, Bycroft M;
JournalJ Mol Biol 2000;299:1113-1119.
PubMed ID10843862
 
Database References
SCOP1e0g
Alignment
Seed alignmentFull alignmentNCBI alignmentMeta sequence alignment
17370629881805
Curation
Source of seed membersPrevious IDsType definitionAuthor of entryNumber in seedNumber in fullAverage Domain LengthAverage IdentityAverage CoverageModel LengthFamily Version
Bateman AFamilyBateman A173706127.60 aa28.00 %31.59 %13511
HMM build information
SequenceDomain
Gathering cutoff:21.521.5
Trusted cutoff:22.022.1
Noise cutoff:21.421.4
HMM build commands
Build methodhmmbuild -o /dev/null HMM SEED
Search methodhmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq